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“Three fungal strains were isolated from sediments of pulp and paper mill in which PF7 reduced colour (27%) and lignin content (24%) of the
effluent selleck products on 5th day. PF7 was identified as Cryptococcus sp. isolate FIST3 on the basis of ITS1 and ITS2 region sequences. The process of decolourization optimized, in shake flask experiments, by Taguchi approach indicated optimum conditions: temperature (30-35 degrees C); shaking condition (125 rpm); dextrose (1.0% w/v); tryptone (0.1% w/v); inoculum size (7.5% w/v); pH (5) and duration (24 h). Overall evaluation criterion (OEC) value before optimization was 32.3. There was 38% improvement in the process with final OEC value, 44.6 +/- 2.02, at optimum conditions. The colour content of the effluent reduced by 50-53% and lignin content 35-40% after treatment at optimum conditions. Variation in pH from5 to 6 had most significant effect on decolourization (72%) while variation in temperature from 30 degrees C to 35 degrees C had Evofosfamide in vitro no effect on the process. Treated effluent was further evaluated for toxicity by alkaline single cell (comet) gel electrophoresis (SCGE) assay using Saccharomyces cerevisiae MTCC 36 as model organism, indicated 45% reduction. The results showed significant reduction in colour, lignin and toxicity of the effluent and this process can be scale up to industrial level. (C)
2009 Published by Elsevier B. V.”
“Severe myoclonic epilepsy of infancy (SMEI)
(OMIM #607208), also known as Dravet syndrome, is a rare genetic disorder characterized by frequent generalized, unilateral clonic or tonic-clonic seizures that begin during the first year of life. Heterozygous de novo mutations in the SCN1A gene, which encodes the neuronal voltage-gated sodium channel alpha subunit type 1 (Nav1.1), are responsible for Dravet syndrome, with a broad spectrum of mutations SNX-5422 in vivo and rearrangements having been reported. In this study, the authors present 4 novel mutations and confirm 2 previously identified mutations in the SCN1A gene found in a cohort of Turkish patients with Dravet syndrome. Mutational analysis of other responsible genes, GABRG2 and PCDH19, were unrevealing. The authors’ findings add to the known spectrum of mutations responsible for this disease phenotype and once again reinforce our understanding of the allelic heterogeneity of this disease.”
“Background: Breast cancer among women is a relatively common with a more favorable expected survival rates than other forms of cancers. This study aimed to determine the improved quality of life for post-mastectomy women through peer education.
Methods: Using pre and post test follow up and control design approach, 99 women with stage I and II of breast cancer diagnosis were followed one year after modified radical mastectomy.