There was considerable variability of patients with chronic conditions across practices, irrespective of whether ICPC-2-diagnoses or prescribed drugs were used to code clinical encounters. Obvious discrepancies between diagnoses and therapies across major LBH589 disease categories existed.
CONCLUSIONS: This study describes the current situation of EMRs in terms
of the ability to measure the burden of chronic conditions in primary care practices. The results illustrate a need of action for this specific topic and the results of this study will be incorporated into the functional specification of EMRs of a planned eHealth project in Swiss primary care.”
“Background: A lower core body temperature set point has been suggested to be a factor that could potentially predispose humans to develop obesity.
Objective: We tested the hypothesis that obese individuals have lower core temperatures than those in normal-weight individuals.
Design: In study 1, nonobese [body mass index (BMI; in kg/m(2)) <30] and obese (BMI >= 30) adults FK506 swallowed wireless core temperature-sensing capsules, and we measured core temperatures continuously for 24 h. In study 2, normal-weight (BMI of 18-25) and obese subjects swallowed temperature-sensing
capsules to measure core temperatures continuously for >= 48 h and kept activity logs. We constructed daily, 24-h core temperature profiles for analysis.
Results: Mean (+/- SE) daily core body temperature did Acadesine not differ significantly between the 35 nonobese and 46 obese subjects (36.92 +/- 0.03 degrees C compared with 36.89 +/- 0.03 degrees C; P = 0.44). Core temperature 24-h profiles did not differ significantly between 11 normal-weight and 19 obese subjects (P = 0.274). Women had a mean core body temperature approximate to 0.23 degrees C greater than that of men (36.99 +/- 0.03 degrees C compared with 36.76 +/- 0.03 degrees C; P < 0.0001).
Conclusions: Obesity is not generally associated with a reduced core body temperature. It may be necessary to study individuals with function-altering mutations in core temperature-regulating
genes to determine whether differences in the core body temperature set point affect the regulation of human body weight. These trials were registered at clinicaltrials.gov as NCT00428987 and NCT00266500. Am J Clin Nutr 2011;93:963-7.”
“This report contains a technical note and 2 case reports of the “”all-on-4″” treatment of the highly resorbed mandible. The use of 4 angled implants directed toward the midline of the mandible at 30 degrees angles provides the advantage of increased implant length and adequate insertion torque for immediate temporization. The technique engages or perforates the inferior border with implants placed in a spaced distribution to avoid fracture of the mandible. The technique is proposed as an alternative to bone graft reconstruction.