Studies should be of the highest technical quality and should pre

Studies should be of the highest technical quality and should present a novel technique, tool, or resource that is applicable to a broad range of questions and that will provide inroads into important questions PF-2341066 in neuroscience. For more specific information and criteria for the NeuroResource format, see our Instructions to Authors (http://www.cell.com/neuron/authors). As always,

if you would like feedback on a paper that you think may be a good fit for this format, we invite you to send a presubmission inquiry to [email protected]. • • • Speaking of names, does Active Zone ring a bell? Those of you paying close attention to your email inboxes over the last several months may know that Cell Press has launched a new e-newsletter—Active Zone—featuring neuroscience content from across the Cell Press and Trends titles and

beyond. Each issue is put together by editors from Neuron, Cell, Current Biology, and Trends journals including Trends in Cognitive Sciences and Trends in Neurosciences, with the aim of spotlighting what we think is interesting, exciting, and fun about neuroscience today. If you are not already receiving the newsletter, we hope you will subscribe. You can browse past issues and sign up to receive new issues at http://www.cell.com/neuron/activezone. In the August issue, we invited scientific luminaries Mike Greenberg, Virginia Lee, Lily and Yuh-Nung Jan, and Yasushi Miyashita to give us their pick for “game changer” papers in learn more their field. We also look back on some of the exciting work in the area of chemical senses and, as we do in each issue, bring you loads of neuroscience-related research and review content from Cell Press—all freely accessible via the links in Active Zone. Check out the Active Zone website and stay tuned for

the next issue in early September. You can also follow ADAMTS5 Active Zone on Twitter @NeuroCellPress. We are eager for feedback and ideas for what you’d like to see in Active Zone, so drop us a line at [email protected]. “
“To establish functionally precise patterns of connectivity, afferent axons must target select regions and, at the end of the line, synapse with specific cellular partners. The cadherins are calcium-dependent cell adhesion molecules. Among the many cadherin types—classical (type I and II) cadherins, desmosomal cadherins, atypical cadherins, and protocadherins—N-cadherin (a classical type I cadherin) has been the most studied and has been implicated in cellular processes ranging from tissue coherence and boundary formation to axon guidance, fasciculation, and laminar targeting (Redies, 2000 and Takeichi, 2007). In addition, cadherins are localized at both pre- and postsynaptic terminals, making them ideal participants in synapse formation (Arikkath and Reichardt, 2008 and Sanes and Yamagata, 2009).

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