Science 2000, 287:1497–1500.PubMedCrossRef 7. Stein M, Bagnoli
F, Halenbeck R, Rappuoli R, Fantl WJ, Covacci A: c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine Vactosertib purchase phosphorylation of the EPIYA motifs. Mol Microbiol 2002, 43:971–980.PubMedCrossRef 8. Szabo I, Brutsche S, Tombola F, Moschioni M, Satin B, Telford JL, et al.: Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity. EMBO J 1999, 18:5517–5527.PubMedCrossRef 9. Tombola F, Morbiato L, Del GG, Rappuoli R, Zoratti M, Smoothened Agonist Papini E: The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia. J Clin Invest 2001, 108:929–937.PubMed 10. Carvajal N, Torres C, Uribe E, Salas find more M: Interaction of arginase with metal ions: studies of the enzyme from human liver and comparison with other arginases. Comp Biochem Physiol B Biochem Mol Biol 1995, 112:153–159.PubMedCrossRef 11. McGee DJ, Zabaleta J,
Viator RJ, Testerman TL, Ochoa AC, Mendz GL: Purification and characterization of Helicobacter pylori arginase, RocF: unique features among the arginase superfamily. Eur J Biochem 2004, 271:1952–1962.PubMedCrossRef 12. Mendz GL, Holmes EM, Ferrero RL: In situ characterization of Helicobacter pylori arginase. Biochim Biophys Acta 1998, 1388:465–477.PubMedCrossRef 13. Langford ML, Zabaleta J, Ochoa AC, Testerman TL, McGee DJ: In vitro and in vivo complementation of the Helicobacter pylori arginase mutant using an intergenic chromosomal site. Helicobacter 2006, 11:477–493.PubMedCrossRef 14. Weeks DL, Eskandari S, Scott
DR, Sachs Histidine ammonia-lyase G: A H + −gated urea channel: the link between Helicobacter pylori urease and gastric colonization. Science 2000, 287:482–485.PubMedCrossRef 15. Gobert AP, McGee DJ, Akhtar M, Mendz GL, Newton JC, Cheng Y, et al.: Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: a strategy for bacterial survival. Proc Natl Acad Sci USA 2001, 98:13844–13849.PubMedCrossRef 16. Zabaleta J, McGee DJ, Zea AH, Hernandez CP, Rodriguez PC, Sierra RA, et al.: Helicobacter pylori arginase inhibits T cell proliferation and reduces the expression of the TCR zeta-chain (CD3zeta). J Immunol 2004, 173:586–593.PubMed 17. Ding SZ, Torok AM, Smith MF, Goldberg JB: Toll-like receptor 2-mediated gene expression in epithelial cells during Helicobacter pylori infection. Helicobacter 2005, 10:193–204.PubMedCrossRef 18. Bussiere FI, Chaturvedi R, Cheng Y, Gobert AP, Asim M, Blumberg DR, et al.: Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation. J Biol Chem 2005, 280:2409–2412.PubMedCrossRef 19. Zhang M, Caragine T, Wang H, Cohen PS, Botchkina G, Soda K, et al.