CrossRefPubMed 26. Rhodius VA, Suh WC, Nonaka G, West J, Gross CA: Conserved and variable functions of the sigmaE stress response in related genomes. PLoS Biol 2006, 4:e2.CrossRefPubMed 27. Bang IS, Frye JG, McClelland M, Velayudhan J, Fang FC: Alternative sigma factor interactions
in Salmonella : sigma and sigma promote antioxidant defences by enhancing sigma levels. Mol Microbiol 2005, 56:811–823.CrossRefPubMed 28. Datsenko KA, Wanner BL: One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 2000, 97:6640–6645.CrossRefPubMed 29. Brown NF, Vallance BA, Coombes BK, Valdez Y, Coburn BA, Finlay BB:Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine. PLoS Pathog 2005, 1:e32.CrossRefPubMed 30. Coombes BK, Brown NF, Kujat-Choy this website S, Vallance BA, Finlay BB: SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells. Microbes Infect 2003, 5:561–570.CrossRefPubMed 31. Beuzon CR, Meresse S, Unsworth KE, Ruiz-Albert J, Garvis S, Waterman SR, Ryder TA, Boucrot E, Holden DW:Salmonella maintains the integrity of its intracellular
selleck chemicals vacuole through the action of SifA. EMBO J 2000, 19:3235–3249.CrossRefPubMed 32. Brumell JH, Tang P, Zaharik ML, Finlay BB: Disruption of the Salmonella -containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infect Immun 2002, 70:3264–3270.CrossRefPubMed 33. Ruiz-Albert J, Mundy R, Yu XJ, Beuzon CR, Holden DW: SseA is a chaperone for the SseB and SseD translocon components of the Salmonella pathogenicity-island-2-encoded type III secretion system. Microbiology 2003, 149:1103–1111.CrossRefPubMed 34. Zurawski DV, Stein MA: SseA acts as the chaperone for the SseB component of the Salmonella Pathogenicity Island 2 translocon. Mol Microbiol 2003, 47:1341–1351.CrossRefPubMed 35. Rytkonen A, Poh J, Garmendia J, Boyle C, Thompson A, Liu M, Freemont P, Hinton JC, Holden DW: SseL, a Salmonella deubiquitinase required for macrophage
Aprepitant killing and virulence. Proc Natl Acad Sci USA 2007, 104:3502–3507.CrossRefPubMed 36. Deiwick J, Nikolaus T, Erdogan S, Hensel M: Environmental regulation of Salmonella pathogenicity island 2 gene expression. Mol Microbiol 1999, 31:1759–1773.CrossRefPubMed 37. Brumell JH, Goosney DL, Finlay BB: SifA, a type III secreted effector of Salmonella typhimurium , directs Salmonella -induced filament (Sif) formation along microtubules. Traffic 2002, 3:407–415.CrossRefPubMed 38. Wray C, Sojka WJ: Experimental Salmonella typhimurium infection in calves. Res Vet Sci 1978, 25:139–143.PubMed Authors’ contributions SEO designed and Idasanutlin performed research, interpreted data and wrote the paper. BKC designed and interpreted research and wrote the paper. Both authors read and approved the final manuscript.