Cognitive debriefing and psychometric analyses demonstrated good internal validity and patient acceptability. The QOL-EA (c) is the first HRQoL instrument developed specifically for MDS patients.”
“Purpose: To investigate the chemical composition and toxicity of the essential oil of Glycosmis parviflora (Sims) Little aerial parts against root-knot nematode and two grain
storage insects (maize weevil and red flour beetle).
Methods: Steam distillation of G. parviflora was carried out using Clavenger apparatus in order to extract its volatile selleck chemicals llc oil. Gas chromatography/mass spectrometric (GC/MS) analysis (HP-5MS column) of the essential oil was performed and the toxicity of the oil determined by contact test.
Results: A total of 37 components comprising 98.7 % of the essential oil were identified, of which (Z)-caryophyllene (20.6 %), methyl isoeugenol (11.1 %), (Z)-beta-ocimene (8.9 %), alpha-cubebene (6.4 %), nerolidol (5.4 %), aromandendrene (4.9 %) and gamma-pyronene (4.7 %) were found to be the major components. The essential oil possessed strong nematicidal
activity against M. incognita GANT61 in vivo with an LC50 value of 92.84 mu g/ml. The essential oil of G. parviflora exhibited strong contact toxicity against S. zeamais and T. castaneum adults with LD50 values of 41.7 and 22.6 mu g/adult, respectively.
Conclusion: The study indicates that the essential oil of G. parviflora aerial parts has a potential for development into a natural insecticide/nematicide for control of nematodes and grain storage insects.”
“SETTING: joint World Health Organization (WHO) projects in Vladimir and Orel regions, Russia.
OBJECTIVE: To study the prevalence of extensively drug-resistant (XDR) tuberculosis (TB).
METHODS: Drug susceptibility testing of second-line drugs (ofloxacin, kanamycin, capreomycin, ethionamide, cycloserine and para-aminosalicylic acid) was performed on isolates from multidrug-resistant Nutlin-3 TB cases from I January to 31 December 2006.
RESULTS: In Orel,
16 (21.3%) of 75 tested isolates were XDR-TB; in Vladimir, 9 (4.9%) of 182 isolates were XDR-TB. Bilateral lung involvement was significantly associated with XDR-TB (prevalence ratio = 2.61, 95%CI 1.01-6.72).
CONCLUSION: XDR-TB has emerged in Russia. It Is crucial to prevent, diagnose and treat TB and MDR-TB more effectively.”
“Nocardia elegans infection in humans is rare and is predominantly associated with pulmonary infections. We describe the first case of N. elegans infection associated with purulent arthritis in humans. The patient was a 66-year-old woman without underlying disease. She had swelling in her left ankle that was increasing in size, but it did not cause the patient substantial pain.