Although in general the NAFLD patients considered asymptomatic, there has no any research study about the

quality of life and it’s affecting factors on NAFLD patients in Indonesia. To find out the factors affecting the quality of life on NAFLD patients. Methods: This is an analytic-observational research with cross-sectional design. Research participants are NAFLD patients in RSUP Dr. Kariadi Semarang. Data were collected via interview using SF-36 CB-839 in vivo RAND questionnaire. Diagnosis of NAFLD and severity by liver biopsy accordingly NAFLD activity score (NAS). Data were then analyzed using Anova or Independent Sample T test. In non-parametric analysis, Mann-Whitney and Kruskal-Wallis tests were performed. Results: 28 participants were enrolled in this research. SF-36 (RAND) score did not differ by sex (p: 0.632), age (p: 0.993), education AZD6244 clinical trial (p: 0.383), marital status (p: 0.488) and NAS (NAFLD activity score) (p: 0.834). Conclusion: SF-36 RAND score did not differ by sex, age, education, marital status and NAFLD activity score. Key Word(s): 1. NAFLD activity score; 2. quality of life Presenting Author: MADHUSUDAN SAHA Additional Authors: ABDULLAH AL MAMUN, SIDDHARTHA

PAUL, KHALEDA BEGUM, AVICK HALDER, FARHANA AFROZ, NADIRA DILRUBA HOQUE Corresponding Author: MADHUSUDAN SAHA Affiliations: Dhaka Medical College, North East Medical College, Dhaka Medical College, Jalalabad Ragib Rabeya Medical College, North East Medical College, Dhaka Medical College Objective: To see incidence of depressive illness among

patients presenting with gastrointestinal symptoms in a tertiary care hospital in North East part of Bangladesh Methods: Consecutive adult patients presenting with various gastrointestinal symptoms were included. In addition to clinic-demographic features all of them were assessed for depressive symptoms MCE using 21 items Hamilton – depression scale. Statistical analysis was done by using SPSS version 16 and chi-square test was performed. P value <0.05 was considered significant. Level of depression was rated taking score 0-7 as normal, 8-13 as mild, 14-18 as moderate, 19-22 as severe and ≥ 23 as very severe. Results: Total 442 patients, age from 18 to 95 years (mean 37.8) with various social, economic and occupational background were included. Among them 281 (63.57%) were male and 161 (36.42%) were female. Mild to very severe depressive illness was found in 276 (63.57%). It was found more common among 25-35 year (68.06%) and >45 years age (67.86%) group. Among them 203 (66.56%) married persons, 109 (67.71%) female, 97 (73%) housewives, 142 (66.99%) and 151 (67.