A laboratory examination and high-resolution computed tomography (HRCT) revealed that he had interstitial pneumonia (IP) with liver dysfunction. Myeloperoxidase-ANCA (MPO-ANCA) was negative. Although
his respiratory condition had become stable after initiation of steroid therapy, liver dysfunction had worsened with selleck chemicals progressive portal hypertension. He died of hepatic insufficiency about three years after the first medical examination.\n\nAutopsy showed that he had vasculitis of medium and small blood vessels of the spleen, lungs, and liver. The final diagnosis was classical polyarteritis nodosa (PAN). Microscopically, non-specific interstitial pneumonia was
identified in the autopsied lung. The pathological findings of the liver were consistent with nodular regenerative hyperplasia (NRH). We report a case of PAN with IP and NRH preceding findings of systemic vasculitis.”
“Objectives: The Internet provides great opportunities for patient healthcare education, but poses risks that inaccurate, outdated or harmful information will be disseminated. Our objective was determine the quality of the information available Y-27632 inhibitor on the internet in relation to oral leukoplakia.\n\nStudy design: Sites were identified using 3 search engines (Google, Yahoo and MSN), and the search term “oral leukoplakia”. The first 100 consecutive
sites in each search were visited and classified. AZD9291 mouse The websites were evaluated for quality of content by using the validated DISCERN rating instrument and the JAMA benchmarks; the existence of the Health on the Net (HON) seal was also registered.\n\nResults: The Google search yielded 54.300 sites for oral leukoplakia, while Yahoo yielded 243.000 and MSN 103.000. We reviewed 21 Google websites, 20 Yahoo websites and 19 MSN. Based on the JAMA benchmarks, only 4 sites (19.1%) met the four criteria in the Google search, versus 2 sites (10%) in the Yahoo and 5 (26.3%) in MSN. With the DISCERN instrument, no site obtained the maximum score, with Google 13 sites presented serious deficiencies (61.9%), in the Yahoo search 14 (70%), and in MSN 15 (78.9%). Lastly, 4 of the Google sites (19.1%), four of the Yahoo sites (20%) and 2 (10.5%) MSN sites presented the HON seal.\n\nConclusions: The quality of the health care information related to oral leukoplakia on the internet is poor.