However, this preliminary evidence of AZD2281 price a link between MP and child OHRQoL needs to be clarified in future studies. In the studied sample, a higher number of missing teeth correlated with an inferior MP in older children. Children with more extensive dental caries rated their oral health less favourably. Moreover, older female children and those who broke the test material into smaller sizes were more likely to report

a lower OHRQoL, probably due to the subjectivity of functional domain and artificial nature of chewable test material, which could have influenced the test sensitivity; however, as MP parameters were inversely correlated, the findings suggested Cell Cycle inhibitor that the time allowed to reduce food appears to be a more influential factor on children’s perception of

oral health than their ability to break down the test material into smaller sizes. Scholarships for Taís de Souza Barbosa from FAPESP (São Paulo Research Foundation) and for Maria Claudia Moraes Tureli from CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). There are no conflicts of interest for any of the authors in this work. The research was approved by the Research Ethics Committee of the Dental School of Piracicaba, State University of Campinas (protocol 021/2006). The authors gratefully acknowledge the financial support from the CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brasília, DF, Brazil) and the volunteers for participating in this research. “
“The oral microbiota has been suggested to function as a reservoir for

several antibiotic not resistance genes, including those encoding resistance to commonly used classes of antibiotics, e.g., beta-lactams, tetracyclines, and macrolides.1, 2, 3, 4 and 5 This is a matter of concern since these antibiotics have been widely recommended to treat oral infectious conditions, including those of endodontic origin.6, 7 and 8 Antibiotics have been proposed for some specific indications, either for systemic or topical use. Systemic use of antibiotics in endodontics is usually indicated for acute apical abscesses associated with systemic involvement like fever and malaise, spreading infections, localized infections in medically compromised patients, prophylaxis for medically compromised patients during routine endodontic therapy, and replantation of avulsed teeth.7 Topical use of antibiotics in the root canal has been recently recommended as final irrigants9 or intracanal medication in the so-called “revascularization” procedures.10 Therefore, selection of the most effective antibiotics to be used for systemic or topical use will depend on a better understanding of the patterns of antibiotic resistance in endodontic bacterial communities and their response to treatment.