Base component of the barrier layer was palm kernel oil, pure or

Base component of the barrier layer was palm kernel oil, pure or in combination with milk fat; micro-milled sugar or skim milk powder served as disperse phase. As compared to control experiments, the formation of fat bloom was significantly reduced for selected barrier layers because

of the reduced transfer of nut oil to the outside of the praline shells. These results indicate that triple-shot depositing is a promising technique for the manufacture of filled chocolate with enhanced physical shelf life. (C) 2008 Elsevier Ltd. All rights reserved.”
“Background: Changes in olfactory functions have been found in many neurodegenerative and psychiatric disorders, including autism spectrum disorders (ASDs). The aim click here of the present study was to evaluate the relationship between olfactory functions (odor-detection thresholds, AZD7762 clinical trial odor identification, and odor preference) and autism severity and sensory-related behavior in children and adolescents with ASD.

Subjects and methods: Our sample consisted of 35 high-functioning patients with ASD (mean age 10.8 +/- 3.6 years, 31 boys). Olfactory

testing (threshold and identification) used the Sniffin’ Sticks test. Odor pleasantness was assessed on a 5-point scale using the Identification part of the Sniffin’ Sticks test. The severity of autistic psychopathology was measured using the Childhood Autism Rating Scale (CARS).

Results:

Using Spearman’s correlation, we found learn more no significant correlations between autism severity (as expressed by total CARS score) and odor-detection thresholds (R=0.144, P=0.409), odor identification (R=0.07, P=0.966), or odor pleasantness (R=-0.046, P=0.794). There was also no significant relationship between CARS item 9 (“”Taste, smell, and touch response and use”") and odor-detection thresholds (R=0.170, P=0.330), odor identification (R=0.282, P=0.100), or odor pleasantness (R=0.017, P=0.923).

Conclusion: We did not find any significant relationship between the severity of autistic psychopathology and olfactory functions.”
“Acute myeloid leukaemia (AML) is a heterogeneous clonal disorder of haematopoietic progenitor cells. Approximately half of all adult AML patients have a normal karyotype (NK-AML) and an intermediate risk prognosis.

To determine the incidence and prognostic significance of NPM1 and FLT3-ITD mutations in a population of patients with NK-AML.

FLT3-ITD and NPM1 mutation status was retrospectively sought in presentation samples from 44 NK-AML patients.

FLT3-ITD and NPM1 mutations were detected in 45.5 and 54.5% of patients, respectively, allowing stratification according to genotype.

FLT3-ITD and NPM1 mutation status can be defined in NK-AML.

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